Metagenomic Assembly using Coverage and Evolutionary distance (MACE)
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چکیده
Recent advances in accuracy and cost of whole-genome shotgun sequencing have opened up various fields of study for biologists. One such field is that of metagenomics – the study of the bacterial biome in a given sample. The human body, for example, has approximately 10 bacterial cells for every native cell, and lack of certain strains may contribute to prevalence of diseases such as obesity, Crohn’s disease, and type 2 diabetes. Although the field of metagenomics is very promising, as with any new field, there are many difficulties with such analyses.
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